Resuscitation Review Blog
Hematology & Transfusion

Disseminated Intravascular Coagulation

Disseminated intravascular coagulation, or DIC, is systemic activation and disruption of coagulation caused by an underlying illness. It can produce both microvascular thrombosis and bleeding.

The absence of visible bleeding does not exclude DIC. In sepsis, the initial problem may be progressive organ dysfunction associated with microvascular injury and thrombosis.

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