High-flow nasal cannula is not simply a comfortable oxygen device.
Its major advantage is flow.
Understanding that flow explains why HFNC can help patients who are failing standard nasal cannula or face mask oxygen.
In respiratory distress, inspiratory flow demand can be very high. If the oxygen device cannot match that demand, the patient entrains room air, and the delivered FiO2 falls.
HFNC can deliver heated, humidified gas at high flow rates.